Fibrosis inhibiting compounds and methods of use thereof in the prevention or treatment of fibrosing diseases

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专利权人:

The Texas A&M University System

发明人:

Gomer, Richard H.,Cox, Nehemiah

申请号：

AU2014324574

公开号：

AU2014324574B2

申请日:

2014.09.29

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

The present disclosure relates to a method of inhibiting fibrocyte or profibrotic macrophage formation by administering a CD209-binding compound or antibody to monocytes in a target location in an amount and for a time sufficient to suppress formation of fibrocytes or profibrotic macrophages from the monocytes. It also relates to compounds and pharmaceutical formulations for use in such methods. The disclosure further relates to compositions usable with these methods and method of detecting CD209-binding compounds and antibodies able to inhibit fibrocyte or profibrotic macrophage formation.

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中国工程科技知识中心

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http://www.ckcest.cn/home/