Sudhakar R. CHINTHARLAPALLI,Anthony S. FISCHL,Victoria Lynn PEEK,Richard A. WALGREN,Sau Chi Betty YAN
申请号:
US15745451
公开号:
US20180207268A1
申请日:
2016.08.10
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a combination of an anti-human VEGFR2 antibody, preferably ramucirumab, and N-(3-fluoro-4-(1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yloxy)phenyl)-1-(4-fluorophenyl)-6-methyl-2-oxo-1,2- dihydropyridine-3-carboxamide, and to methods of using the combination to treat certain disorders, such as gastric cancer.