A patch for replacement of a portion of bladder wall following partial cystectomy includes a multi-layered membrane of soft silicone with a thickness of about 600 microns so as to be sufficiently elastic to be able to withstand the dilatations due to expansion and deflation of the bladder, a surface layer of texturized silicone that is arranged to face an outside of a bladder to reduce a risk of adhesion of fibrotic capsule, and an inner coating of pyrolytic turbostatic carbon that is arranged to face an inside of the bladder.