The invention relates to 5-cyano-3-methyl-pyridine-2-carboxylic acid [3-((3R,6R)-5-amino-3,6-dimethyl-6-trifiuoromethyl-3,6-dihydro- 2H-(1,4)oxazin-3-yl)-4-fluoro-phenyl))-amide in crystalline form, to its preparation, its medical use and to medicaments comprising said compound in crystalline form for use in the treatment of Alzheimers disease.La invención se refiere a la [3-((3R,6R)-5-amino-3,6-dimetil-6- trifluoro-metil-3,6-dihidro-2H-(1 ,4-oxazin-3-iI)-4-fluoro-fenil)- amida del ácido 5-ciano-3-metil-piridin-2-carboxílico: (Ver Formula) en forma cristalina, a su preparación, a su uso médico, y a medicamentos que comprenden este compuesto en forma cristalina para usarse en el tratamiento de la enfermedad de Alzheimer.