GANSERT, Jennifer, Lorraine,BHATTA, Sumita, Shankar,WOODARD, Joseph, Paul,CHA, Edward
申请号：
AU2018314227
公开号：
AU2018314227A8
申请日:
2018.08.06
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
Provided herein are methods of treating a subject with triple negative breast cancer or colorectal cancer. In exemplary embodiments, the method comprises administering to the subject a combination of an oncolytic virus, such as talimogene laherparepvec, and an anti-PD-Ll antibody, such as atezolizumab. In exemplary aspects, the oncolytic virus is administered to the subject at an initial dose followed by a second dose, wherein the initial dose is lower than the second dose. In exemplary aspects, the oncolytic virus is intrahepatically administered to the subject.
