Amide compounds (I) and their enantiomers, diastereomers, mixtures and salts, preferably with organic or inorganic acids or bases, are new. Amide compounds of formula (R 5>；-A-R 4>；-B1-R 3>；-A-D1-Y1-N(R 2>；)-SO 2-R 1>；) (I) and their enantiomers, diastereomers, mixtures or salts, preferably with organic or inorganic acids or bases, are new. A : a bond, 1-4C-alkyl or-CH 2-C(O)-； B1 : a bond, 1-3C-alkyl, -O- or -C(O)-； D1 : -N(R 2>；)-C(=O)- or -C(=O)-N(R 2>；)-； Y1 : 1-6C alkyl (optionally substituted by R 2>；, where methylene group is additionally substituted by Y2)； Y2 : -O-, -S-, -S(O)-, -N(R 2>；)-, -N(R 2>；)-C(O)-, -C(O)-N(R 2>；)-, -C(O)-, -CH(aryl)-, 3-6C-cycloalkylene or-S(O) 2-； R 1>；3-7C-cycloalkyl- or aryl-, heteroaryl- or aryl-1-3C-alkyl- (substituted by 1-3 residues of R1a)； R1a : H, F, Cl, Br, I, 1-3C-alkyl-, F 3C-, HO-, 1-3C-alkyl-O- or 1-3C-alkyl-O-2-4C-alkylene-O-； R 2>；H or 1-3C-alkyl- (where each methylene group is substituted with up to 2 F and each methyl group is substituted with up to 3 F), or (H 3C-C(O)-)； R 3>；1-6C-alkyl, mono-, di- or tri-substituted 3-6C-cycloalkyl, mono- or di-substituted 5-7C-cycloalkenyl (which is condensed over the unsaturated bond with a phenyl ring), N(R 2>；), mono- or di-substituted hetero(aryl), mono- or di-substituted saturated 4-7-membered heterocyclic ring, mono- or di-substituted unsaturated 5-7-membered heterocyclic ring (which is condensed over the unsaturated bond with one or two phenyl rings), or mono- or di-substituted saturated 8-10-membered aza-heterobicycle (all optionally substituted by R3a), or -O-； R 4>；mono- or di-substituted hetero(aryl), mono- or di-substituted 4-7-membered saturated heterocyclic ring, mono- or di-substituted saturated 8-10-membered diaza-heterobicyclic ring, mono- or d- substituted 5-7-membered unsaturated heterocyclic ring, which is condensed over the unsaturated bond with one or two phenyl rings, a saturated 9-11-membered diaza-spirocycle (all optiona
