Disclosed is a food or pharmaceutical composition comprising kakrol (Momordica dioica Roxb.). Kakrol, which is a vegetable originally produced in Bangladesh, resembles balsam pear. The food or pharmaceutical composition is useful for the treatment of a disease or condition associated with lipid metabolism, hyperlipemia (including primary (familial, sporadic) and secondary hyperlipemia, hypercholesterolemia and hyper(LDL)cholesteremia), arteriosclerosis, ischemic heart disease (including angina pectoris and cardiac infarction), cerebrovascular disease (including cerebral infarction and cerebral hemorrhage) or lifestyle-related disease. The food or pharmaceutical composition can prevent the absorption of a lipid.