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IMICIMODE COMPOSITION
专利权人:
ИНК. (US);ДОУ ФАРМАСЬЮТИКАЛ САЙЕНСИЗ
发明人:
ВИНКЛ Гэрет (US),ОСБОРН Дэвид В. (US)
申请号:
RU2010123618/15
公开号:
RU2010123618A
申请日:
2009.01.14
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. A solution containing one or more polar solvents, in addition to water, imiquimod or an analogue thereof, dissolved in said one or more solvents, a hydrogen bond forming compound dissolved in said one or more solvents, and possibly water, said solution containing 30 % wt. or less water. ! 2. The solution according to claim 1, characterized in that it essentially does not contain water. ! 3. The solution according to claim 1, characterized in that it contains water. ! 4. The solution according to claim 3, characterized in that the concentration of water contained in the specified solution is less than 5 times the concentration of imiquimod or its analogue contained in the specified solution. ! 5. The solution according to claim 3, characterized in that it contains less than 25% water. ! 6. The solution according to claim 5, characterized in that it contains less than 20% water. ! 7. The solution according to claim 6, characterized in that it contains less than 15% water. ! 8. The solution according to claim 1, characterized in that it contains a low concentration of fatty acids, liquid at room temperature. ! 9. The solution of claim 8, characterized in that it essentially does not contain fatty acids, liquid at room temperature. ! 10. The solution according to claim 1, characterized in that the molar ratio of imiquimod or its analogue to the compound forming hydrogen bonds is from 4: 1 to 1: 4. ! 11. The solution according to claim 1, characterized in that the said compound forming hydrogen bonds is selected from the group consisting of alpha hydroxy acids, beta hydroxy acids, alkyl sarcosinates, anionic PEGylated derivatives of dimethicone, anionic surfactants - oleyl ethers, anionic surfactants - laureth ethers, cyclic acids and cyclic acids1. Раствор, содержащий один или более полярных растворителей, кроме воды, имиквимод или его аналог, растворенный в указанных одном или более растворителях, соединение, образующее водородные связи, растворенное в указанных одн
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