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Dérivés de 17.béta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane utilisés comme anti-inflammatoires
专利权人:
Glaxo Group Limited
发明人:
申请号:
EP08020059.5
公开号:
EP2067784A3
申请日:
2001.08.03
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
There are provided according to the invention compounds of formula (I)whereinR1 represents C1-6 alkyl or C1-6 haloalkyl;R2 represents -C(=O)-aryl or -C(=O)-heteroaryl;R3 represents hydrogen, methyl (which may be in either the α or β configuration) or methylene;R4 and R5 are the same or different and each represents hydrogen or halogen; and----- represents a single or a double bond;and salts and solvates thereof.There are also provided processes for preparing compounds of formula (I) and use of the compounds in therapy especially in the treatment of inflammatory and allergic conditions.
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