Emmanuel A. Theodorakis;Ta-Hsiang Chao;Venkat Rami Reddy Macherla;Michael A. Palladino;Young-Ger Suh
发明人:
Michael A. Palladino,Emmanuel A. Theodorakis,Venkat Rami Reddy Macherla,Ta-Hsiang Chao,Young-Ger Suh
申请号:
US13007573
公开号:
US08133915B2
申请日:
2011.01.14
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Described herein are chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. Also described are methods of synthesizing natural products and novel, structurally-related chemical compounds. More particularly, disclosed are new analogs of and processes for the preparation of compounds and pharmaceutical compositions thereof useful in the treatment of, for example, inflammation, cancer, multiple myeloma, cachexia, cardiovascular disease, anti-infectious, diabetes, otitis media, sinusitis and transplant rejection.