The John Hopkins University;Rensselaer Polytechnic Institute
发明人:
Andres Hurtado,Ryan James Gilbert,Han Bing Wang,Jared M. Cregg,Michael E. Mullins,Martin Oudega
申请号：
US16524473
公开号：
US20190350688A1
申请日:
2019.07.29
申请国别(地区):
US
年份:
2019
代理人:
摘要：
One aspect of the invention provides a three-dimensional scaffold including at least one layer of highly-aligned fibers. The at least one layer of highly-aligned fibers is curved in a direction substantially perpendicular to a general direction of the fibers. Another aspect of the invention provides a method for fabricating a three-dimensional scaffold. The method includes: electro spinning a plurality of fibers to produce at least one layer of highly-aligned fibers and forming the at least one layer of highly-aligned fibers into a three-dimensional scaffold without disturbing the alignment of the highly-aligned polymer fibers. A further aspect of the invention provides methods for using a three-dimensional scaffold to treat nerve or spinal cord injury.
