METHOD OF MANUFACTURING POROUS THREE-DIMENSIONAL MICRO/NANOFIBROUS SCAFFOLD USING ELECTROHYDRODYNAMIC PROCESS AND POROUS THREE-DIMENSIONAL MICRO/NANOFIBROUS SCAFFOLD MANUFACTURED THEREBY
Provided are a method of manufacturing a porous three-dimensional microfiber, more particularly, a micro/nanofibrous scaffold using an electrohydrodynamic (EHD) process and a porous three-dimensional micro/nanofibrous scaffold manufactured thereby.According to the method, the porous three-dimensional micro/nanofibrous scaffold, in which a pore structure is controlled by a process of phase changing an initial jet manufactured through the EHD process from a gas phase to a liquid phase using a liquid collector having a low surface tension, may be manufactured.In addition, the scaffold manufactured by the manufacturing method according to the present invention has a very similar structure to an extracellular matrix (ECM), and is considerably improved in a pore structure and porosity, thereby increasing an cell attached area and enabling cells to permeate into the scaffold, and thus can provide an optimal environment for in vitro or in vivo cell growth to proliferate the cells.
