Memorial Sloan Kettering Cancer Center;Eureka Therapeutics, Inc.
发明人:
申请号：
EP16808304.6
公开号：
EP3307319A4
申请日:
2016.06.09
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
Described herein are antibodies, fragments thereof and multi-specific binding agents that bind an Epstein-Barr virus (EBV) latent membrane protein 2 (LMP2) peptide presented by HLA class I molecules, in particular, HLA-A02. Also provided herein are methods of using the same or compositions thereof for the detection, prevention and/or therapeutic treatment of diseases characterized by expression of an EBV-LMP2 peptide presented by HLA-A02, in particular, Burkit's lymphoma, Hodgkin's lymphoma and nasopharyngeal carcinoma.
