YU-HSIN LIN;YIH-HUANG HSIEH;YU-CHEN LIN;WEI HAN LEE;CHENG DER TONY YU;CHENG-CHI WANG;I-JU CHEN;OBI PHARMA INC.;NAN-HSUAN WANG;CHUNG-HAO CHANG
发明人:
CHENG-CHI WANG,WEI HAN LEE,NAN-HSUAN WANG,CHUNG-HAO CHANG,YIH-HUANG HSIEH,CHENG DER TONY YU,YU-HSIN LIN,I-JU CHEN,YU-CHEN LIN
申请号：
IL23978515
公开号：
IL239785A
申请日:
2015.07.05
申请国别(地区):
IL
年份:
2018
代理人:
摘要：
The present invention provides vaccines comprising carbohydrate antigen conjugated to a diphtheria toxin (DT) as a carrier protein, wherein the ratio of the number of carbohydrate antigen molecule to the carrier protein molecule is higher than 5:1. Also disclosed herein is a novel saponin adjuvant and methods to inhibit cancer cells, by administering an effective amount of the vaccine disclose herein.
