MILLENNIUM PHARMACEUTICALS INC.;STEPAN VYSKOCIL;IAN G. ARMITAGE;REENU CHOPRA;MARTIN IAN COOPER;MARIANNE LANGSTON;STEVEN P. LANGSTON
发明人:
STEPAN VYSKOCIL,IAN G. ARMITAGE,REENU CHOPRA,MARTIN IAN COOPER,MARIANNE LANGSTON,STEVEN P. LANGSTON
申请号:
IL21620111
公开号:
IL216201A
申请日:
2011.11.08
申请国别(地区):
IL
年份:
2015
代理人:
摘要:
Disclosed is a compound of formula ( I ): crystalline forms thereof, and solvates thereof; pharmaceutical compositions comprising a pharmaceutically effective amount of the compound of formula ( I ), or a crystalline form thereof, or a solvate thereof, and a pharmaceutically acceptable carrier or diluent; and the use of a compound of formula ( I ), or a crystalline form thereof, or a solvate thereof, for treating a patient suffering from, or subject to, a pathological condition capable of being ameliorated by inhibiting an E1 activating enzyme, particularly NAE, including, e.g., cancer.