The present invention comprises a novel method for producing a heterocyclic derivative compound of formula (I)； a novel intermediate compound used in the above-mentioned production method； and a compound of formula (I) at a dose of more than 2 mg and 10 mg or less, A composition for treating or preventing hyperuricemia, gout disease, nephritis, chronic renal failure, renal stone disease, uremic disease, urolithiasis, or a uric acid-related disease, which is orally administered once a day； and It relates to a novel hydrochloride hydrate of the compound of formula (I).本発明は、式（Ｉ）の複素環誘導体化合物の新規の製造方法；前記製造方法に使用される新規の中間体化合物；式（Ｉ）の化合物を２ｍｇ超～１０ｍｇ以下の投与用量で含み、１日１回経口投与される、高尿酸血症、痛風疾患、腎炎、慢性腎不全、腎結石症、尿毒症、尿路結石症、又は尿酸に関連する疾患の治療又は予防用組成物；及び新規の式（Ｉ）の化合物の塩酸塩１．５水和物に関する。
