A single-needle medicine mixer, dual hard ports, and a soft infusion bag (1). The medicine mixer comprises a base (2), a medicine mixing passage (7), a medicine mixing cup (3), and a puncture needle (5). The base (2), the medicine mixing passage (7), and the medicine mixing cup (3) are integrally formed, the medicine mixing cup (3) consists of a cup wall (3-1) and a cup bottom (3-2), the lower end of the medicine mixing passage (7) penetrates through the base (2), and the upper end penetrates through the cup bottom (3-1); the upper end of the medicine mixing passage (7) is provided with the puncture needle (5) having a hollow passage, the lower end of the puncture needle (5) is connected to the upper end of the medicine mixing passage (7) in a sealing way, and the hollow passage is communicated with the medicine mixing passage (7); the medicine mixer also comprises a sealing membrane (9), the sealing membrane (9) being welded at a cup opening of the medicine mixing cup (3) in a press welding way so as to seal the medicine mixing cup (3); and the sealing membrane (9) is an easy-to-tear membrane which can still be basically kept smooth after sterilization of a wet-heating terminal. The medicine mixer is convenient to use and has no potential safety hazard.L'invention concerne un mélangeur de médicament à aiguille unique, des orifices durs doubles et une poche de perfusion souple (1). Le mélangeur de médicament comprend une base (2), un passage de mélange de médicament (7), une coupelle de mélange de médicament (3) et une aiguille de ponction (5). La base (2), le passage de mélange de médicament (7) et la coupelle de mélange de médicament (3) sont formés d'un seul tenant, la coupelle de mélange de médicament (3) comporte une paroi de coupelle (3-1) et un fond de coupelle (3-2), l'extrémité inférieure du passage de mélange de médicament (7) pénètre à travers la base (2), et l'extrémité supérieure pénètre à travers le fond de coupelle (3-1) ; l'extrémité supérieure du pa