PR13.5 PROMOTER FOR ROBUST T-CELL AND ANTIBODY RESPONSES

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专利权人:

Bavarian Nordic A/S

发明人:

Robin Steigerwald,Kay Brinkmann

申请号：

US15821035

公开号：

US20180111966A1

申请日:

2017.11.22

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The invention encompasses recombinant poxviruses, preferably modified Vaccinia Ankara (MVA) viruses, comprising a Pr13.5 promoter operably linked to a nucleotide sequence encoding an antigen and uses thereof. The invention is drawn to compositions and methods for the induction of strong CD8 T cell and antibody responses to a specific antigen(s) by administering one or more immunizations of the recombinant MVA to a mammal, preferably a human.

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中国工程科技知识中心

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