The present Disclosure provides compounds that are inhibitors of Tyrosine Kinases, particularly inhibitors of the tyrosine kinase Bruton (BTK), and thereforeThey are useful for the treatment of diseases that can be treated through inhibition of BTK such as cancer, autoimmune diseases, inflammatory and thromboembolic.Also provided are Pharmaceutical compositions containing these compounds and processes for preparing such compounds.La presente divulgacion proporciona compuestos que son inhibidores de tirosina-cinasas, en particular inhibidores de la tirosina-cinasa de Bruton (BTK), y, por lo tanto, son utiles para el tratamiento de enfermedades que se pueden tratar mediante la inhibicion de BTK tales como el cancer, enfermedades autoinmunitarias, inflamatorias y tromboembolicas. Tambien se proporcionan composiciones farmaceuticas que contienen tales compuestos y procesos para preparar tales compuestos.