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Handling and Control System for Expandable Electrodes of A Handpiece for Use in an Electro-Poration Process
专利权人:
IGEA S.p.A.
发明人:
Ruggero Cadossi,Donata Marazzi,Claudio Bertacchini,Francesca De Terlizzi,Mattia Ronchetti
申请号:
US15638849
公开号:
US20180001085A1
申请日:
2017.06.30
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A handling and control system for expandable electrodes of a handpiece is provided that includes a plurality of flexible electrodes made of elastic cables carried by a support assembly with needle-shaped front portions that protrude from the support assembly and move in a three-dimensional space under the push of actuators. An electronic control device performs the following functions: a) providing a command to the actuators to perform an initial handling of each cable according to an initial step Δh performing an axial advancement of the front portion with respect to the second proximal end and a distancing of the front portion from the axis H; b) determining for each pair of electrodes the spacing or distance li, measured along a direction perpendicular to the axis, between the tips of the front portions of the pair of electrodes; c) determining a voltage V as a function of the spacing li, V=f(li) and applying to each electrode a pulsed signal having maximum voltage equal to the calculated value V; e) repeating the steps a), b) and c) for a plurality n of steps k successive to the initial one so that the active portions of the electrodes move in space in a three-dimensional application area becoming distanced from each other; the voltage applied to the electrodes increasing linearly with the increasing of the spacing so as to generate an electric field which ensures in the application area complete electro-poration of tissue.
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