The United States of America; as represented by the Secretary; Department of Health & Human Servic
发明人:
Xiaowu Pang,Andrew I. Dayton,Mingjie Zhang
申请号:
US14923134
公开号:
US20160243214A1
申请日:
2015.10.26
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention discloses the construction of dengue virus subgenomic replicons containing large deletions in the structural region (C-preM-E) of the genome, which replicons are useful as vaccines to protect against dengue virus infection.