A multi-modality imaging system including first and second imaging modality units having respective field of views (FOVs) that are spaced apart from each other. The imaging system also having a positioning system that includes an imaging pallet. The pallet has an elongated support body that includes first and second portions that extend lengthwise along the support body. The first portion is shaped for imaging within the FOV of the first modality unit, and the second portion is shaped for imaging within the FOV of the second modality unit. The first and second portions are shaped differently than each other. The positioning system is configured to position the first portion of the pallet within the FOV of the first modality unit and configured to position the second portion of the pallet within the FOV of the second modality unit.