The present invention relates to a pharmaceutical composition containing a DUSP1 inhibitor. The pharmaceutical composition containing the DUSP1 inhibitor, according to the present invention, inhibits DUSP1 through an allosteric mechanism, thereby resolving the problem of inhibitors targeting an active site, and is effective in the prevention or treatment of DUSP1 enzyme-associated diseases such as hepatitis C, depression, and cancer such as liver cancer, breast cancer, and pancreatic cancer. Particularly, the DUSP1 inhibitor according to the present invention directly acts on the growth of neurons, thereby being very effective in the treatment of depression.La présente invention concerne une composition pharmaceutique contenant un inhibiteur de DUSP1. La composition pharmaceutique contenant l'inhibiteur de DUSP1, selon la présente invention, inhibe DUSP1 par l'intermédiaire d'un mécanisme allostérique, de façon à résoudre le problème d'inhibiteurs ciblant un site actif, et qui est efficace dans la prévention ou le traitement de maladies associées à l'enzyme DUSP1 telles que l'hépatite C, la dépression et le cancer tel que le cancer du foie, le cancer du sein et le cancer du pancréas. En particulier, l'inhibiteur de DUSP1 selon la présente invention agit directement sur la croissance de neurones, de façon à être très efficace dans le traitement de la dépression.본 발명은 DUSP1 저해제를 함유하는 약제학적 조성물에 관한 것으로, 본 발명에 따른 DUSP1 저해제를 함유하는 약제학적 조성물은 DUSP1을 알로스테릭 기작으로 저해하기 때문에 활성 부위를 표적으로 하는 저해제가 갖는 문제점을 해결할 수 있으며, 간암, 유방암, 췌장암 등의 암, C형 간염, 우울증 등 DUSP1 효소가 관여하는 질병의 예방 또는 치료에 효과적이다. 특히, 본 발명에 따른 DUSP1 저해제는 신경세포 성장에 직접적으로 작용하기 때문에 우울증 치료에 매우 효과적이다.
