COMPOSES ET COMPOSITIONS UTILISES COMME INHIBITEURS DE PROTEINES KINASES

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专利权人:

IRM LLC

发明人:

REN, PINGDA,WANG, XIA,ZHANG, GUOBAO,DING, QIANG,YOU, SHULI,ZHANG, QIONG,CHOPIUK, GREG,ALBAUGH, PAMELA A.,SIM, TAEBO,GRAY, NATHANAEL SCHIANDER

申请号：

CA2567662

公开号：

CA2567662C

申请日:

2005.06.09

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

The invention provides a novel class of compounds of formula I:(see formula I)wherein R1, R2, R3, R4, m and n are as defined in the claims, pharmaceuticalcompositions comprising such compounds and methods of using such compounds totreat or prevent diseases or disorders associated with abnormal or deregulatedkinase activity, particularly diseases or disorders that involve abnormalactivation ofthe Abl, BCR-Abl, PDGF-R, trkB, c-SRC, BMX, FGFR3, b-RAF, SGK, Tie2, Lck,JNK2.alpha.2, MKK4, c-RAF, MKK6, SAPK2.alpha. and SAPK2.beta. kinases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/