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1H-benzimidazole-4-carboxamides substituted with phenyl at the 2-position are potent PARP inhibitors
专利权人:
Jianchun Gong;Virajkumar B. Gandhi;Vincent L. Giranda;Sheela A. Thomas;Thomas D. Penning;Gui-Dong Zhu
发明人:
Thomas D. Penning,Sheela A. Thomas,Gui-Dong Zhu,Virajkumar B. Gandhi,Jianchun Gong,Vincent L. Giranda
申请号:
US11536994
公开号:
US08697736B2
申请日:
2006.09.29
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Compound having formula (I)inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds having formula (I), methods of treatment comprising compounds having formula (I), and methods of inhibiting the PARP enzyme comprising compounds having formula (I).
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