Methods and systems for simulating a phonocardiogram (PCG) signal that includes an anomalous condition are provided. The method generates pressure and flow signals from a lumped-parameter heart model responsive to anomaly parameters. The anomaly parameters represent the anomalous condition. A timing profile or the timing profile and an amplitude profile are extracted from at least one of the generated pressure and flow signals. An anomalous signal is generated using the anomaly parameters and the extracted timing profile or timing profile and amplitude profile. The anomalous signal is time-aligned and combined with a predetermined non-anomalous signal to represent the PCG signal.
