LLP2A-BISPHOSPHONATE CONJUGATES FOR OSTEOPOROSIS TREATMENT

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专利权人:

Nancy Lane;Kit S. Lam;Wei Yao;Ruiwu Liu

发明人:

Kit S. Lam,Ruiwu Liu,Wei Yao,Nancy Lane

申请号：

US13820362

公开号：

US20140056855A1

申请日:

2012.01.19

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention provides compounds and pharmaceutical compositions of a peptidomimetic ligand, e.g. LLP2A, conjugated with a bisphosphonate drug, e.g. Alendronate. The compounds and pharmaceutical compositions of the present invention are useful in the treatment of osteoporosis and for the promotion of bone growth due to their specificity for the α4β1 integrin on mesenchymal stem cells and for the surface of bone.

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中国工程科技知识中心

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http://www.ckcest.cn/home/