Michael Friedman;Rakefet Czernimski;Silvio Gutkind;Doron Steinberg;Irith Gati;Zakhar Nudelman
发明人:
Michael Friedman,Rakefet Czernimski,Silvio Gutkind,Doron Steinberg,Irith Gati,Zakhar Nudelman
申请号:
US13391756
公开号:
US10485792B2
申请日:
2010.08.25
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention discloses a method of treating a head and neck cancer or preventing the development of pre-malignant lesions to this cancer, by administering locally to the oral cavity, a sustained release drug delivery system comprising a drug for the treatment of this cancer or for the prevention of said lesions, and at least one polymer, such that said system is attached to a surface in the oral cavity and remains attached thereto for at least 1 hour, accompanied by release of the drug and maintaining an effective therapeutic concentration thereof in the cavity, for at least 1 hour. Further are disclosed a sustained release drug delivery system and a liquid precursor varnish composition to this system.