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FLUOROALKYL DIBENZOAZEPINONE COMPOUNDS
专利权人:
发明人:
Ashvinikumar V. Gavai
申请号:
US14429951
公开号:
US20150218104A1
申请日:
2013.09.20
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed are compounds of Formula (I): wherein R1 is CH2CH2CF3 or CH2CH2CH3 R2 is CH2CH2CF3, CH2CH2CH3, CH2(cyclopropyl), phenyl, or R3 is H Ra, Rb, y, and z are defined herein. Also disclosed are methods of using such compounds to inhibit the Notch receptor, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as cancer.
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