An aiding and guiding instrument for surgical sutures includes a frame that can be rested on a patient proximate to a wound to be sutured and/or to flaps of body tissue and/or prosthetic tissue to be mutually fixed. The frame defines, on the other side from the area configured to be placed on the patient, a plurality of raised portions arranged in series. At least some of the raised portions are mutually spaced to define respective seats for accommodating blocks. In the gap between each block and each contiguous raised portion, it is possible to temporarily stably accommodate a portion of a suture thread. At least one portion of the frame, associated with the raised portions and seats, can be plastically deformed to maintain the shape obtained following a deformation imparted by a user, and freely select the frame shape, and of the mutual arrangement of the raised portions and blocks.