Composition comprising a purified extract isolated from Pseudolysimachion rotundum var. subintegrum containing abundant amount of active ingredient or the compounds isolated therefrom, as an active ingredient for treating a chronic obstructive pulmonary disease and the use thereof
YUNGJIN PHARMACEUTICAL CO., LTD;KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
发明人:
Yongnam Lee,Ji-seok Yoo,Dae-hee Shin,Byung-hwan Ryoo,Kyung Seop Ahn,Sei Ryang Oh,Hyeong Kyu Lee,In Sik Shin,Doo Young Kim,Ok-Kyoung Kwon,Hyuk Hwan Song,Seung Hyung Kim,SuUi Lee
申请号:
US14780503
公开号:
US09655871B2
申请日:
2014.04.09
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A composition comprising a purified extract isolated from Pseudolysimachion rotundum var. subintegrum containing abundant amount of active ingredient or the compounds isolated therefrom as an active ingredient for treating a chronic obstructive pulmonary disease and the use thereof. Inventive purified extract and compounds showed potent anti-COPD activity without beta-2-receptor agonistic response through various in vivo tests as well as in vitro test. Therefore, it can be used as the therapeutics or functional health food for treating and preventing chronic obstructive pulmonary disease (COPD).