The present invention provides a blood circuit capable ofautomatically performing priming for safe treatments.The blood circuit includes: a hemofilter (56) purifying blood; ablood removal line that has an end connected to an inlet of thehemofilter (56) and that consists of a first blood removal line (84), asecond blood removal line (88), and a third blood removal line (89); ablood return line that has an end connected to an outlet of thehemofilter (56) and that consists of the first blood return line (92) andthe second blood return line (94); and an anticoagulant (bypass) line(90) reducing a difference between (a) a pressure of a priming fluidflowing in the blood removal line and (b) a pressure of the primingfluid flowing in the blood return line.