Arthur F. Kluge;Chris Oalmann;Krishna K. Murthi;Siya Ram;Jianxing Huang;Zhongguo Wang;Nicholas Bockovich
发明人:
Nicholas Bockovich,Arthur F. Kluge,Chris Oalmann,Krishna K. Murthi,Siya Ram,Zhongguo Wang,Jianxing Huang
申请号:
US10584485
公开号:
US08097619B2
申请日:
2004.12.21
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention pertains to novel cyclin dependent kinase inhibitors (cdks) and specifically, but not exclusively, as inhibitors of cdk/cyclin complexes. As described herein, the inhibitors of this invention are capable of inhibiting the cell-cycle machinery and consequently may be useful in modulating cell-cycle progression, untimately controlling cell growth and differentiation. Such compounds would be useful for treating subjects having disorders associated with excessive cell proliferation.