therapeutic agent for enhancing skin properties comprising a morphinan derivative or any of its pharmacologically permissible acid addition salts as an active ingredient.
KOICHIRO TAKESHITA,MASAHIRO YAMASHITA,NAOKI ANDO,SHINJI ONA
申请号:
BRPI0817804
公开号:
BRPI0817804A2
申请日:
2008.10.03
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The object of this invention is to provide a novel medicine useful for therapy to improve the skin properties such as skin drying, skin roughening and the skin darkening involved in hyperkeratosis (thickened keratin layer) via a skin moisture retaining effect against the decline of the skin functions brought about by various causes. This invention provides a skin property-improving therapeutic agent comprising a compound having a specific morphinan skeleton typified by a compound 1 represented by the following formula (II) or any of its pharmacologically permissible acid addition salts as an active ingredient.