Pyridylamide compounds of Formula: (I) wherein R1 is -C1-4alkyl or saturated monocyclic cycloalkyl m is 1 or 2 X is N or CH Y is N or CR3 Ra is -H, -Z-Ar, -CH2NRbRc, -CN, -CO2C1-4alkyl, -CO2H, or -CONRbRc where Rb and Rc are each independently -H or -C1-4alkyl and R2 is -H or -Z-Ar with the proviso that one of X and Y is N and one of Ra and R2 is -Z-Ar where Z is O or S and Ar is a phenyl or monocyclic heteroaryl group unsubstituted or substituted with one, two, or three R3 substituents where each R3 substituent is independently selected from the group consisting of: halo, -C1-4alkyl, -OH1 -OC1-4alkyl, -SC1-4alkyl, -CN, -CONRdRe, and -NO2 where Rd and Re are each independently -H or -C1-4alkyl are histamine H3 receptor modulators useful in the treatment of histamine H3 receptor-mediated1 diseases.Certains composés de pyridyl amide substitués faisant lobjet de cette invention sont des modulateurs des récepteurs de lhistamine H3.
