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Indole (Indolizine) derivatives and their pharmaceutical use
专利权人:
LTD.;KISSEI PHARMACEUTICAL CO.
发明人:
SHIMIZU, KAZUO,IIZUKA, MASATO,TAKIGAWA, YASUISHI
申请号:
TW99109853
公开号:
TWI471325B
申请日:
2010.03.31
申请国别(地区):
TW
年份:
2015
代理人:
摘要:
The present invention provides compounds useful as agents for the prevention or treatment of a disease associated with abnormal serum uric acid level and the like. That is, the present invention relates to indolizine derivatives represented by the following formula (I) having xanthine oxidase inhibitory activities and useful as agents for the prevention or treatment of a disease associated with abnormality of serum uric acid level, prodrugs thereof, salts thereof or the like. In the formula, ring U represents aryl or heteroaryl; R 1 represents halogen, a hydroxy group or the like; R 2 represents halogen, a hydroxy group, alkyl, alkoxy, alkyl substituted by fluorine, alkoxy substituted by fluorine or the like; m represents a number from 0 to 2; n represents a number from 0 to 3; and R 3 represents hydrogen, fluorine or the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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