Simon McGurk,Padma Narayan,Clare Medendorp,George Wu,Stephen Ruddy,Heidi Kempinski,Alistair Stewart
申请号：
US16584149
公开号：
US20200016142A1
申请日:
2019.09.26
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to pharmaceutical capsule compositions comprising the compound niraparib as an active pharmaceutical ingredient, suitable for oral administration as well as to methods for their preparation. Also described herein are capsule formulations containing niraparib formed by the disclosed methods, and therapeutic uses of such capsule formulations for treating various disorders and conditions. The niraparib is distributed with substantial uniformity throughout a pharmaceutically acceptable carrier of the capsule formulations and exhibit good long-term stability and dissolution properties.
