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Terconazole composition and method
专利权人:
Robert J. Borgman
发明人:
Robert J. Borgman,James E. Juul
申请号:
US11519303
公开号:
US09211286B2
申请日:
2006.09.12
申请国别(地区):
US
年份:
2015
代理人:
摘要:
An aqueous terconazole composition comprises at least about 0.4 percent by weight of terconazole dissolved in water, and a terconazole crystallization-inhibiting amount of an organic acid. Preferably the organic acid is a water soluble alkyl carboxylic acid, a polybasic organic acid, or a combination thereof. The composition is free from terconazole crystals at an ambient temperature of about 20° C. Methods of preparing the composition are also described. The compositions provide for improved therapeutic release of terconazole.
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