Sergei V. Kotenko,Joan Durbin,Viralkumar Rameshkumar Davra
申请号:
US16604666
公开号:
US20200071375A1
申请日:
2018.05.01
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Fusion molecules composed of a type I interferon protein or portion thereof and a type III interferon protein or portion thereof, pharmaceutical compositions containing the fusion molecules, and methods for their use in inhibiting infection, inhibiting or treating cancer, inducing signaling of transcription of IFN-stimulated genes through an IFN-αR2 chain in a subject suffering from an infection which degrades or downregulates an IFN-αR1 chain, and treating various diseases or conditions are provided.