Heather D. Maynard,Natalie Boehnke,Samantha J. Paluck
申请号:
US16469786
公开号:
US20200085964A1
申请日:
2017.12.19
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Non-crushable pill formulations and methods of using the formulations are disclosed. A non-crushable pill formulation for preventing unintended use of a drug, comprising a polymer, the polymer forming a polymer backbone of the complex; cross-linkers, the cross-linkers connecting the polymer backbone through covalently bonding to form at least one inner cavity within the complex; and the drug, the drug being trapped either covalently or non-covalently in the at least one inner cavity within the complex, wherein the drug is protected from releasing outside of the complex.