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FORMULATIONS CONTAINING A SOMATOSTATIN RECEPTOR AGONIST
专利权人:
CAMURUS AB
发明人:
Justas BARAUSKAS,Catalin NISTOR,Markus JOHNSSON
申请号:
US16361622
公开号:
US20190262419A1
申请日:
2019.03.22
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to pre-formulations comprising:a) at least one di-acyl lipid;b) at least one phospholipid;c) at least one biocompatible, organic solvent;d) an alkyl ammonium EDTA salt; ande) at least one somatostatin receptor agonist;wherein the pre-formulation has a water content in the range of 0 to 1.0 wt %.The invention further relates to methods of treatment comprising administration of such pre-formulations, to pre-filled administration devices and kits containing the formulations, to the use of an alkylammonium EDTA salt to reduce the decomposition of the lipid components and/or any active agent contained within the pre-formulation.
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