N-oxazolidinylmethyl-substituted (benzo)thiophene carboxamides (I) and their salts, hydrates and prodrugs are new. N-oxazolidinylmethyl-substituted (benzo)thiophene carboxamides of formula (I) and their salts, hydrates and prodrugs are new. [Image] R 1>； : optionally benzo-fused thiophene, optionally substituted one or more times； R 2>； : any selected organic group； R 3>；-R 8>； : same or different hydrogen or 1-6C alkyl. Excluded are compounds where R 2>； = phenyl (optionally substituted once or more) and all of R 3>；-R 8>； are hydrogen. Independent claims are also included for the following: (1) preparation of (I)； and (2) pharmaceutical composition containing (I), optionally also auxiliaries and carriers. ACTIVITY : Anticoagulant； cardiant； anti-anginal； vasotropic； thrombolytic； cerebroprotective； antiarthritic； antiarteriosclerotic； cytostatic； nootropic； neuroprotective. Test details are described but no results given. MECHANISM OF ACTION : Coagulation factor Xa Inhibitor.
