IN VIVO GENE ENGINEERING WITH ADENOVIRAL VECTORS

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专利权人:

发明人:

申请号：

EP15785973.7

公开号：

EP3137120A4

申请日:

2015.05.01

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention provides recombinant nucleic acid expression cassetie and helper dependent adenovirus, where the expression cassettes utilize a miRNA based system for controlling expression of nucleases in helper dependent adenoviral viral producer cells, thus permitting production and use for in in vivo gene editing in CD34+ cells.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/