Georgia Tech Research Corporation;University of Louisville Research Foundation, Inc.
发明人:
Shirwan, Haval,Garcia, Andres J.,Yolcu, Esma S.,Zhao, Hong,Headen, Devon
申请号：
AU2018230474
公开号：
AU2018230474A1
申请日:
2018.03.09
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
Described herein are FasL-engineered biomaterials, as well as methods of making and using such FasL-engineered biomaterials, such as for immunomodulation, such as for inducing immunosuppression and specific immune tolerance, such as for preventing or reducing the risks of rejection of cellular or tissue grafts and/or the treatment of autoimmune disorders such as Type I diabetes. In specific embodiments, the FasL-engineered biomaterials are biotinylated microgels bound to SA-FasL.
