Monoclonal antibodies against the PBP2-a protein and homologous sequences for the treatment of infections by and immunodiagnostics of bacteria of the firmicutes phylum
Senna, Jose Procopio Moreno,Queiroz, Joao Luiz Sampaio,Batoreu, Nadia Maria,Teixeira, Maria Da Gloria Martins
申请号：
AU2010282162
公开号：
AU2010282162A1
申请日:
2010.08.10
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention relates to monoclonal antibodies capable of recognising and binding to the PBP2-a protein and to other proteins having sequences homologous to PBP2-a, including pathogenic species such as the methyciline-resistant (MRSA), coagulase-negative, and , and any other bacteria containing the PBP2-a protein or homologous sequences. The invention also relates to the use of the monoclonal antibodies capable of recognising and binding to the PBP2-a protein and to other proteins having sequences homologous to PBP2-a in a complementary immunodiagnostic test for detecting resistance to beta-lactam antibiotics.
