HAYDON, DAVID JOHN,CZAPLEWSKI, LLOYD GEORGE,PALMER, NICHOLAS JOHN,MITCHELL, DALE ROBERT,ATHERALL, JOHN FREDERICK,STEELE, CHRISTOPHER RICHARD,LADDUWAHETTY, TAMARA
申请号：
CA2655403
公开号：
CA2655403C
申请日:
2007.06.21
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Compounds of formula (I) have antibacterial activity: wherein: m is 0 or 1 ； Q is hydrogen or cyclopropyl； AIk is an optionally substituted, divalent C1-C6 alkylene, alkenylene or alkynylene radical which may contain an ether (-O-), thioether (-S-) or amino (-NR)- link, wherein R is hydrogen, -CN or C1-C3 alkyl； X is -C(=O)NR6-, -S(O)NR6-, -C(=O)O- or -S(=O)O- wherein R6 is hydrogen, optionally substituted C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, -Cyc, or -( C1-C3 alkyl)-Cyc wherein Cyc is optionally substituted monocyclic carbocyclic or heterocyclic having 3-7 ring atoms； Z is N or CH, or CF； R2 and R3 are as defined in the description.
