University of Pittsburgh—Of the Commonwealth System of Higher Education
发明人:
Carol A. Feghali-Bostwick,Yukie Yamaguchi
申请号:
US15152468
公开号:
US09556252B2
申请日:
2016.05.11
申请国别(地区):
US
年份:
2017
代理人:
摘要:
C-terminal endostatin polypeptides are disclosed herein. Polynucleotides encoding these polypeptide, host cells transformed with the polynucleotides, and methods of using these polypeptides and polynucleotides are disclosed. Uses of these polypeptide, polynucleotides and expression vectors include the treatment of fibrosis in a subject. Thus, methods are provided for treating fibrosis, including fibrosis of the skin and/or the lung.