David William Griggs;Melanie Boyle;Maureen Jeri Bourner;Mark Allen Moffa;Gerald Fries Casperson;William Dean Joy;Richard Allen Mazzarella;Richard David Head;Christopher Todd Bauer;Ralph Raymond Minter
发明人:
Christopher Todd Bauer,Maureen Jeri Bourner,Melanie Boyle,Gerald Fries Casperson,David William Griggs,Richard David Head,William Dean Joy,Richard Allen Mazzarella,Ralph Raymond Minter,Mark Allen Moffa
申请号：
US13079726
公开号：
US08974781B2
申请日:
2011.04.04
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to P-cadherin, and that function to inhibit P-cadherin. The invention also relates to heavy and light chain immunoglobulins derived from human P-cadherin antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human P-cadherin antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions. The invention also relates to transgenic animals or plants comprising nucleic acid molecules of the present invention.
