Abide Therapeutics, Inc.;The Scripps Research Institute
发明人:
Justin S. Cisar,Cheryl A. Grice,Todd K. Jones,Micah J. Niphakis,Jae Won Chang,Kenneth M. Lum,Benjamin F. Cravatt
申请号:
US14599105
公开号:
US09133148B2
申请日:
2015.01.16
申请国别(地区):
US
年份:
2015
代理人:
摘要:
This disclosure provides piperazine carbamates and compositions which may be modulators of MAGL and/or ABHD6 and their use as medicinal agents, processes for their preparation, and pharmaceutical compositions that include disclosed piperazine carbamates as at least one active agent. The disclosure also provides for method of treating a patient in need thereof, where the patient is suffering from indications such as pain, solid tumor cancer and/or obesity comprising administering a disclosed compound or composition.