Methods and compositions for reducing amyloid beta levels

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专利权人:

Li Gan;Lennart Mucke

发明人:

Li Gan,Lennart Mucke

申请号：

US12447241

公开号：

US08420613B2

申请日:

2007.11.15

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The present invention provides methods for reducing the level of amyloid beta protein in a cell or tissue, the methods generally involving contacting the cell or tissue with an agent that reduces cystatin C levels and/or activity. The present invention provides methods for treating Alzheimer's disease (AD), and methods for treating cerebral angiopathy, in an individual, the methods generally involving administering to an individual having AD a therapeutically effective amount of an agent that reduces cystatin C levels and/or activity. The present invention further provides methods for identifying an agent that reduces cystatin C levels and/or activity.

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